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TTK21
CAS No. 709676-56-2
TTK21( CBP-p300 activator TTK21 )
Catalog No. M15723 CAS No. 709676-56-2
TTK21 (CBP-p300 activator TTK21) is a small molecule activator of CBP/p300 histone acetyltransferase activity with a maximal effect at a concentration of 275 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 117 | In Stock |
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| 5MG | 107 | In Stock |
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| 10MG | 161 | In Stock |
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| 25MG | 325 | In Stock |
|
| 50MG | 477 | In Stock |
|
| 100MG | 714 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1451 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTTK21
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NoteResearch use only, not for human use.
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Brief DescriptionTTK21 (CBP-p300 activator TTK21) is a small molecule activator of CBP/p300 histone acetyltransferase activity with a maximal effect at a concentration of 275 uM.
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DescriptionTTK21 (CBP-p300 activator TTK21) is a small molecule activator of CBP/p300 histone acetyltransferase activity with a maximal effect at a concentration of 275 uM; induces acetylation of histones H3 and H4 in vitro but not H2B and H2A; promotes neurogenesis and extends memory duration in adult mice, promotes regeneration and sprouting of sensory and motor axons, as well as recovery of sensory and motor functions in both the mouse and rat model of spinal cord injury.
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In Vitro——
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In Vivo——
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SynonymsCBP-p300 activator TTK21
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PathwayChromatin/Epigenetic
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TargetHAT
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RecptorHAT
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Research Area——
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Indication——
Chemical Information
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CAS Number709676-56-2
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Formula Weight357.757
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Molecular FormulaC17H15ClF3NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (279.52 mM)
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SMILESCCCOC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F
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Chemical NameN-(4-chloro-3-trifluoromethyl-phenyl)-2-N-propoxy-benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chatterjee S, et al. J Neurosci. 2013 Jun 26;33(26):10698-712.
2. Hutson TH, et al. Sci Transl Med. 2019 Apr 10;11(487). pii: eaaw2064.
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