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Escin
CAS No. 6805-41-0
Escin( —— )
Catalog No. M15597 CAS No. 6805-41-0
Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 28 | In Stock |
|
| 100MG | 36 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 83 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEscin
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NoteResearch use only, not for human use.
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Brief DescriptionPentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
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DescriptionPentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
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In VitroWestern Blot Analysis Cell Line:OGD/R and rt-PA stimulated bEnd.3 cells Concentration:0.1, 0.5 and 1 μg/mL Incubation Time:24 h Result:Upregulated the expression of ZO-1 and Occludin.
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In VivoAnimal Model:Con A-induced immune-mediated hepatitis mice Dosage:10 mg/kg Administration:p.o., 4 days Result:Decreased the peak activities of ALT (p?Synonyms——PathwayOthersTargetOther TargetsRecptorOthersResearch AreaOther IndicationsIndication——
Chemical Information
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CAS Number6805-41-0
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Formula Weight1131.28
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Molecular FormulaC55H86O24
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Purity>98% (HPLC)
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SolubilitySoluble in Water
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SMILESCC=C(C)C(=O)OC1C([C@@]2(C(C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CCC([C@]5(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yu Z, Su P. Pharmazie. 2013 Jun;68(6):428-30.
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BMS-986224
BMS-986224 is an orally active, potent, and selective APJ receptor agonist. BMS-986224 has the potential to study heart failure.
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Substance P (6-11)/H...
Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (Substance P ).Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect.
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Egg yolk phosphatidy...
Lecithins, egg can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
