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Perhexiline maleate
CAS No. 6724-53-4
Perhexiline maleate( WSM 3978G )
Catalog No. M15566 CAS No. 6724-53-4
Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 92 | In Stock |
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| 2MG | 48 | In Stock |
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| 5MG | 78 | In Stock |
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| 10MG | 118 | In Stock |
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| 25MG | 213 | In Stock |
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| 50MG | 309 | In Stock |
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| 100MG | 462 | In Stock |
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| 200MG | 631 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePerhexiline maleate
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NoteResearch use only, not for human use.
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Brief DescriptionPerhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).
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DescriptionPerhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2); promotes HER3 ablation through receptor internalization and inhibits tumor growth; activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.Hypertension Phase 2 Clinical.
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In VitroCell Viability Assay Cell Line:HepG2 cells Concentration:5, 10, 15, 25 μM Incubation Time:2, 4, 6 h Result:Induced time- and concentration-dependent cytotoxicity in hepatic cells.Western Blot Analysis Cell Line:HepG2 cells Concentration:5, 10, 15, 25 μM Incubation Time:2 h Result:Reduced Bcl-2 and Mcl-1 level, and increased Bad level.
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In VivoAnimal Model:Orthotopic glioblastoma mouse modelDosage:80 mg/kg Administration:Oral gavage, for 3 days. Result:Reduces tumor size (MR imaging) and improves in overall survival.
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SynonymsWSM 3978G
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCardiovascular Disease
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IndicationHypertension
Chemical Information
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CAS Number6724-53-4
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Formula Weight393.568
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Molecular FormulaC23H39NO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Ethanol : 25 mg/mL (63.52 mM)
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SMILESC1CCC(CC1)C(CC2CCCCN2)C3CCCCC3.C(=CC(=O)O)C(=O)O
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Chemical Name2-(2,2-dicyclohexylethyl)-piperidine maleate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Guo Y, et al. J Clin Invest. 2015 Oct 1;125(10):3819-30.
2. Hamdan M, et al. Pharmacol Res. 2001 Aug;44(2):99-104.
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