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Dextromethorphan HBr monohydrate
CAS No. 6700-34-1
Dextromethorphan HBr monohydrate( DXM | D-Methorphan )
Catalog No. M15560 CAS No. 6700-34-1
Methyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDextromethorphan HBr monohydrate
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NoteResearch use only, not for human use.
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Brief DescriptionMethyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center.
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DescriptionMethyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
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In Vitro——
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In Vivo——
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SynonymsDXM | D-Methorphan
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptornAChR| δ-opioid receptor| κ-opioid receptor| μ-opioid receptor
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number6700-34-1
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Formula Weight370.32
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Molecular FormulaC18H25NO·HBr·H2O
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Purity>98% (HPLC)
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SolubilityWater: 24mg/mL
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SMILESCN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)OC.O.Br
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Thomas BR, et al. J Pharm Biomed Anal. 1994 Jan;12(1):85-90.
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