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Dextromethorphan HBr monohydrate

CAS No. 6700-34-1

Dextromethorphan HBr monohydrate( DXM | D-Methorphan )

Catalog No. M15560 CAS No. 6700-34-1

Methyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dextromethorphan HBr monohydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Methyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center.
  • Description
    Methyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DXM | D-Methorphan
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    nAChR| δ-opioid receptor| κ-opioid receptor| μ-opioid receptor
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    6700-34-1
  • Formula Weight
    370.32
  • Molecular Formula
    C18H25NO·HBr·H2O
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 24mg/mL
  • SMILES
    CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)OC.O.Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Thomas BR, et al. J Pharm Biomed Anal. 1994 Jan;12(1):85-90.
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