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Home - Products - Cell Cycle/DNA Damage - PARP - BGP-15

BGP-15

CAS No. 66611-37-8

BGP-15( BGP 15 | BGP15 )

Catalog No. M15540 CAS No. 66611-37-8

A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 30 In Stock
5MG 28 In Stock
10MG 45 In Stock
25MG 90 In Stock
50MG 147 In Stock
100MG 239 In Stock
200MG 352 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    BGP-15
  • Note
    Research use only, not for human use.
  • Brief Description
    A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro.
  • Description
    A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro; has no effect on HSP90 levels, markedly increases the phosphorylation of HSF1 and expression of HSF1 and HSP72 in adipocytes and muscle cells; protects against obesity-induced insulin resistance and orally active; alleviates ventilation-induced diaphragm dysfunction associated with HSP72 induction and PARP-1 inhibition.Diabetes Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BGP 15 | BGP15
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    PARP
  • Research Area
    Metabolic Disease
  • Indication
    Diabetes

Chemical Information

  • CAS Number
    66611-37-8
  • Formula Weight
    351.272
  • Molecular Formula
    C14H24Cl2N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 11.33 mg/mL
  • SMILES
    C1CCN(CC1)CC(CON=C(C2=CN=CC=C2)N)O.Cl.Cl
  • Chemical Name
    3-Pyridinecarboximidamide, N-[2-hydroxy-3-(1-piperidinyl)propoxy]-, hydrochloride (1:2)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Salah H, et al. Sci Transl Med. 2016 Aug 3;8(350):350ra103. 2. Chung J, et al. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44. 3. Racz I, et al. Biochem Pharmacol. 2002 Mar 15;63(6):1099-111. 4. Kardon T, et al. Anticancer Res. 2006 Mar-Apr;26(2A):1023-8.
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