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RU-24969
CAS No. 66611-26-5
RU-24969( RU24969 | RU 24969 )
Catalog No. M15539 CAS No. 66611-26-5
A potent, selective agonist of 5-HT1A and 5-HT1B receptors, with preference for 5-HT1B.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 63 | In Stock |
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| 5MG | 53 | In Stock |
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| 10MG | 81 | In Stock |
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| 50MG | 257 | In Stock |
|
| 100MG | 383 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRU-24969
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective agonist of 5-HT1A and 5-HT1B receptors, with preference for 5-HT1B.
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DescriptionA potent, selective agonist of 5-HT1A and 5-HT1B receptors, with preference for 5-HT1B; inhibited the rate of synthesis of 5-HT in rat brain by about 50% (10mg/kg)
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In VitroRU 24969 (10 μM) reduces K+-stimulated release of [3H]-5-HT from ratfrontalcortex slices in vitro.
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In VivoRU 24969 (0.03-3.0 mg/kg; s.c.) dose-dependently decreases water consumption in water deprived rats.RU 24969 (0.3-3.0 mg/kg; s.c.) dose-dependently increases forward locomotion. Animal Model:Male Sprague-Dawley rats Dosage:0.03, 0.3, 1.0, 3.0 mg/kg Administration:A single s.c.Result:Decreased water consumption significantly at dose of 0.3, 1.0, and 3.0 mg/kg.
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SynonymsRU24969 | RU 24969
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number66611-26-5
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Formula Weight228.2896
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Molecular FormulaC14H16N2O
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESCOC1=CC2=C(NC=C2C3=CCNCC3)C=C1
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Chemical Name1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Green AR, et al. Neuropharmacology. 1984 Jun;23(6):655-61.
2. Harrison AA, et al. Psychopharmacology (Berl). 1999 Jan;141(3):242-50.
3. Parsons LH, et al. J Neurosci. 1998 Dec 1;18(23):10078-89.
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