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Milveterol
CAS No. 652990-07-3
Milveterol( GSK 159797 )
Catalog No. M15483 CAS No. 652990-07-3
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMilveterol
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NoteResearch use only, not for human use.
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Brief DescriptionMilveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays.
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DescriptionMilveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold); demonstrates high potency in vitro and long duration of action in a guinea pig model of bronchoprotection.Asthma Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsGSK 159797
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PathwayGPCR/G Protein
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TargetAdrenergic Receptor
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RecptorAdrenergic Receptor
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Research AreaInflammation/Immunology
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IndicationAsthma
Chemical Information
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CAS Number652990-07-3
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Formula Weight435.524
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Molecular FormulaC25H29N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=CC=C(C=C1)C(CNC2=CC=C(C=C2)CCNCC(C3=CC(=C(C=C3)O)NC=O)O)O
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Chemical NameN-(2-hydroxy-5-((R)-1-hydroxy-2-((4-(((R)-2-hydroxy-2-phenylethyl)amino)phenethyl)amino)ethyl)phenyl)formamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jacobsen JR, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1213-8.
2. Fuso L, et al. Curr Med Chem. 2013;20(12):1477-95.
3. Jacobsen JR, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2625-30.
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