Butoconazole nitrate( (±)-Butoconazole | RS-35887 )

Catalog No. M15461 CAS No. 64872-77-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Butoconazole nitrate
Note

Research use only, not for human use.
Brief Description

Butoconazole nitrate is an anti-fungal agent for IL-2, TNFα, IFN and GM-CSF with IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively.
Description

Butoconazole nitrate is an anti-fungal agent for IL-2, TNFα, IFN and GM-CSF with IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively.(In Vitro):Imidazoles generally inhibit the conversion of lanosterol to ergosterol, resulting in a change in fungal cell membrane lipid composition. This structural change alters cell permeability and, ultimately, results in the osmotic disruption or growth inhibition of the fungal cell.
In Vitro

Imidazoles generally inhibit the conversion of lanosterol to ergosterol, resulting in a change in fungal cell membrane lipid composition. This structural change alters cell permeability and, ultimately, results in the osmotic disruption or growth inhibition of the fungal cell.
In Vivo

——
Synonyms

(±)-Butoconazole | RS-35887
Pathway

Endocrinology/Hormones
Target

Estrogen Receptor/ERR
Recptor

ER
Research Area

Infection
Indication

——

CAS Number

64872-77-1
Formula Weight

474.79
Molecular Formula

C19H18Cl3N3O3S
Purity

>98% (HPLC)
Solubility

DMSO: 95 mg/mL (200.08 mM)
SMILES

ClC1=C(SC(CCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=CC=C1.O[N+]([O-])=O
Chemical Name

1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole nitrate

1.Pfaller MA, et al. Diagn Microbiol Infect Dis. 1990 Jan-Feb;13(1):31-5.

Calculator

molnova catalog