Zoxazolamine

Research use only, not for human use.

Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.

Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.

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Zoxazolamine is widely used for a pharmacologic test that serves as a convenient indicator of changes in cytochrome P-450 activity in rodents. The time-averaged serum clearance determined from tested concentrations data is 7.22±1.01 mL/min/kg for Zoxazolamine. Infusion of Zoxazolamine to righting reflex (LRR) at three different rates shows increasing Zoxazolamine concentration in serum and brain at the onset of the effect with increasing infusion rates. When the Zoxazolamine infusion is continued for 5 min beyond the onset of LRR, the concentrations of Zoxazolamine in the cerebrospinal fluid (CSF) at the offset of LRR are essentially identical to the onset concentrations.

2-Amino-5-chlorobenzoxazole | Contrazole | NSC 24995

Others

Other Targets

Others

Other Indications

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61-80-3

168.58

C7H5ClN2O

>98% (HPLC)

Ethanol: 34 mg/mL (201.68 mM); DMSO: 34 mg/mL (201.68 mM)

c1cc2c(cc1Cl)nc(o2)N

2-Benzoxazolamine, 5-chloro- (9CI)

(-20℃)

With Ice Pack

≥ 2 years