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Imagabalin
CAS No. 610300-07-7
Imagabalin( PD 0332334 | PD 332334 )
Catalog No. M15291 CAS No. 610300-07-7
Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
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| 50MG | 2142 | Get Quote |
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| 100MG | 2790 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameImagabalin
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NoteResearch use only, not for human use.
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Brief DescriptionImagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.
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DescriptionImagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2; demonstrated preclinical efficacy of anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity for the treatment of generalized anxiety disorder.Anxiety Phase 3 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsPD 0332334 | PD 332334
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research AreaNeurological Disease
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IndicationAnxiety
Chemical Information
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CAS Number610300-07-7
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Formula Weight173.253
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Molecular FormulaC9H19NO2
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Purity>98% (HPLC)
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Solubility——
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SMILESCCC[C@@H](C)C[C@H](N)CC(O)=O
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Chemical Name(3S,5R)-3-amino-5-methyloctanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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SR33805
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)Acute treatment with SR33805 restored the MI-altered cell shortening without affecting the Ca(2+) transient amplitude, suggesting an increase of myofilament Ca(2+) sensitivity in MI myocytes.?
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(S)-(-)-Bay-K-8644
(S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.
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Azumolene
Azumolene1.EU4093 (azumolene sodium) is a direct acting, skeletal muscle relaxant with structural similarities to dantrolene sodium in that the para-nitro phenyl group of dantrolene sodium is replaced by a para-bromo phenyl group.?2.?The effect of EU4093 on the twitch of the intact rat soleus preparation is nearly maximal at a dose of 20 mg kg-1.?
