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Imagabalin hydrochloride
CAS No. 610300-00-0
Imagabalin hydrochloride( PD-0332334 | PD-332334 )
Catalog No. M15290 CAS No. 610300-00-0
Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameImagabalin hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionImagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.
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DescriptionImagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2; demonstrated preclinical efficacy of anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity for the treatment of generalized anxiety disorder.Anxiety Phase 3 Discontinued.
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In Vitro——
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In Vivoβ-Amino Acid Imagabalin Hydrochloride had been in phase III clinical trials for the treatment of generalised anxiety disorders. However, this research has been discontinued. β-Amino Acid Imagabalin Hydrochloride had been also in phase I clinical trials for the treatment of chronic kidney disease.
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SynonymsPD-0332334 | PD-332334
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number610300-00-0
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Formula Weight209.714
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Molecular FormulaC9H20ClNO2
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Purity>98% (HPLC)
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Solubility——
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SMILESCCC[C@@H](C)C[C@H](N)CC(O)=O.[H]Cl
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Chemical Name(3S,5R)-3-amino-5-methyloctanoic acid hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Quintero JE, et al. Brain Res. 2011 Jul 15;1401:1-9.
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