Miltefosine
CAS No. 58066-85-6
Miltefosine( HePC )
Catalog No. M15130 CAS No. 58066-85-6
Miltefosine is used for the treatment of visceral and cutaneous leishmaniasis, and is undergoing clinical trials for this use in several other countries.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 28 | In Stock |
|
| 100MG | 37 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 83 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMiltefosine
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NoteResearch use only, not for human use.
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Brief DescriptionMiltefosine is used for the treatment of visceral and cutaneous leishmaniasis, and is undergoing clinical trials for this use in several other countries.
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DescriptionMiltefosine is used for the treatment of visceral and cutaneous leishmaniasis, and is undergoing clinical trials for this use in several other countries. Several medical agents have some efficacy against visceral or cutaneous leishmaniasis, however a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis.
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In Vitro——
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In Vivo——
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SynonymsHePC
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number58066-85-6
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Formula Weight407.58
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Molecular FormulaC21H46NO4P
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Purity>98% (HPLC)
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SolubilityEthanol: 82 mg/mL (201.19 mM); Water: 82 mg/mL (201.19 mM)
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SMILESO=P(OCCCCCCCCCCCCCCCC)([O-])OCC[N+](C)(C)C
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Chemical Namehexadecyl (2-(trimethylammonio)ethyl) phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PKC β pseudosubstrat...
Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM). Consists of amino acids 19 - 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide.
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Clitorin
Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.
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Protein Kinase C 19-...
Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.
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