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TBBz
CAS No. 577779-57-8
TBBz( Casein Kinase II Inhibitor XII | TBBz )
Catalog No. M15112 CAS No. 577779-57-8
A potent, selective and ATP-competitive CK2 inhibitor with Ki of 0.5-1 uM; weakly inhibits CK1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTBBz
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective and ATP-competitive CK2 inhibitor with Ki of 0.5-1 uM; weakly inhibits CK1.
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DescriptionA potent, selective and ATP-competitive CK2 inhibitor with Ki of 0.5-1 uM; weakly inhibits CK1 (about 100-fold less potent), and has no activity for PKA and PKC; decreases the activity of GBM-initiating cell regulator β-catenin, reduces cell growth, decreases tumor size, and increases survival rates in GBM xenograft mouse models.
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In Vitro——
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In Vivo——
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SynonymsCasein Kinase II Inhibitor XII | TBBz
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PathwayMetabolic Enzyme/Protease
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TargetCasein Kinase
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RecptorCasein Kinase
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Research Area——
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Indication——
Chemical Information
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CAS Number577779-57-8
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Formula Weight433.72
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Molecular FormulaC7H2N2Br4
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=NC2=C(N1)C(=C(C(=C2Br)Br)Br)Br
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Chemical Name4,5,6,7-Tetrabromo-1H-benzimidazole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zień P, et al. Biochem Biophys Res Commun. 2003 Jun 20;306(1):129-33.
2. Zien P, et al. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):271-80.
3. Nitta RT, et al. Oncogene. 2015 Jul;34(28):3688-99.
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