Chlorhexidine

Research use only, not for human use.

Chlorhexidine is an antibacterial used as an antiseptic and for other applications.

Chlorhexidine is an antibacterial used as an antiseptic and for other applications. (In Vivo):Chlorhexidine gluconate (ip) reduces postoperative intra-abdominal infection in mice at the end of colon surgery.

——

Chlorhexidine gluconate (ip) reduces postoperative intra-abdominal infection in mice at the end of colon surgery. Animal Model:One hundred and eighty male Imprinting Control Region (ICR) mice at 6 to8-wk-old (body weight, 25 ± 3 g) were randomized to six groups.Dosage:Chlorhexidine gluconate 0.05%, and Chlorhexidine gluconate 0.025%.Administration:One-time intraperitoneal injection.Result:A total of 48 mice (26.7%) developed postoperative intra-abdominal abscesses. Mice that had Chlorhexidine gluconate 0.05% lavage had significantly lower incidence of postoperative intra-abdominal abscesses compared with that of group D mice that had saline lavage only (P = 0.0113). Microscopic peritoneal fibrosis occurred significantly more among group E mice that had Chlorhexidine gluconate 0.05% lavage compared with group D mice that had saline lavage only (P = < 0.005).

Chlorhexidine | EC 200-238-7

Microbiology/Virology

Antifection

HNMT| CAT

Infection

——

55-56-1

505.45

C22H30Cl2N10

>98% (HPLC)

Soluble in DMSO

N=C(NC1=CC=C(Cl)C=C1)NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N

2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-

(-20℃)

With Ice Pack

≥ 2 years