Shikonin( (+-)-Alkannin, (+-)-Shikonin, Arnebin-4, Shikonin )

Catalog No. M14984 CAS No. 54952-43-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Shikonin
Note

Research use only, not for human use.
Brief Description

Alkannin is a natural dye that is obtained from the extracts of plants from the borage family Alkanna tinctoria that are found in the south of France.
Description

Alkannin is a natural dye that is obtained from the extracts of plants from the borage family Alkanna tinctoria that are found in the south of France. The dye is used as a food coloring and in cosmetics. It is used as a red-brown food additive in regions such as Australia.
In Vitro

Shikonin shows a similar potency toward drug-sensitive cancer cell lines (MCF-7 and HEK293) and their drug-resistant lines overexpressing P-glycoprotein, Bcl-2, or Bcl-xL, which account for most of the clinical cancer drug resistance.
In Vivo

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Synonyms

(+-)-Alkannin, (+-)-Shikonin, Arnebin-4, Shikonin
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

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CAS Number

54952-43-1
Formula Weight

288.29
Molecular Formula

C16H16O5
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

CC(=CCC(C1=CC(=O)c2c(ccc(c2C1=O)O)O)O)C
Chemical Name

1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9CI)

1. Zhao Q, et al. Int J Y. 2015 Sep 15;137(6):1446-56.

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