ISRIB

CAS No. 548470-11-7

ISRIB( —— )

Catalog No. M14973 CAS No. 548470-11-7

ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 83 In Stock
5MG 46 In Stock
10MG 74 In Stock
25MG 149 In Stock
50MG 246 In Stock
100MG 362 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ISRIB
  • Note
    Research use only, not for human use.
  • Brief Description
    ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
  • Description
    ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    ERK
  • Recptor
    PERK
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    548470-11-7
  • Formula Weight
    451.34
  • Molecular Formula
    C22H24Cl2N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    ClC1=CC=C(OCC(=O)NC2CCC(CC2)NC(=O)COC2=CC=C(Cl)C=C2)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sidrauski C, et al. Elife. 2013, 2, e00498.
molnova catalog
related products
  • GSK2656157

    GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM in a cell-free assay.

  • DB07268

    DB07268 is a potent and selective JNK1 inhibitor.

  • Patritumab

    Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-small cell lung cancer.