Acetohydroxamic acid
CAS No. 546-88-3
Acetohydroxamic acid( AHA | NSC 5073 | NSC 176136 | NSC 408425 )
Catalog No. M14966 CAS No. 546-88-3
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | 27 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 50 | In Stock |
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| 1G | 73 | In Stock |
|
Biological Information
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Product NameAcetohydroxamic acid
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NoteResearch use only, not for human use.
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Brief DescriptionAcetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea.
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DescriptionAcetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
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In Vitro——
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In Vivo——
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SynonymsAHA | NSC 5073 | NSC 176136 | NSC 408425
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number546-88-3
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Formula Weight75.07
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Molecular FormulaC2H5NO2
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Purity>98% (HPLC)
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SolubilitySoluble in Water
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SMILESCC(NO)=O
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Chemical NameAcetamide, N-hydroxy- (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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NSC 405020
NSC 405020 is a noncatalytic inhibitor of MT1-MMP, directly interacts with PEX domain of MT1-MMP, affects PEX homodimerization but not catalytic activity of MT1-MMP.
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Apigenin-7-glucuroni...
Apigenin-7-glucuronide possesses multiple activities including antioxidant anti-inflammatory and aldose reductase inhibitory activities it can inhibit MMP activities (IC50s: 12.87 22.39 17.52 0.27 μM for MMP-3 MMP-8 MMP-9 MMP-13 respectively).
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MMP2-IN-2
MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively .
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