CP-724714 (b)

CAS No. 537705-08-1

CP-724714 (b)( —— )

Catalog No. M14915 CAS No. 537705-08-1

CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 In Stock
50MG 1782 In Stock
100MG 2250 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CP-724714 (b)
  • Note
    Research use only, not for human use.
  • Brief Description
    CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM.
  • Description
    CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays. Phase 2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    HER2/ErbB2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    537705-08-1
  • Formula Weight
    469.53
  • Molecular Formula
    C27H27N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    N/A
  • SMILES
    CCOC(=O)NC/C=C/C1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OC4=CN=C(C=C4)C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1 Jani JP, et al. Cancer Res, 2007, 67(20), 9887-9893. 2 Feng B, et al. Toxicol Sci, 2009, 108(2), 492-500.
molnova catalog
related products
  • EGFR Inhibitor

    EGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.

  • Mobocertinib

    Mobocertinib is a potent ?inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent.

  • PF-06747775

    A potent, selective, irreversible EGFR mutants with IC50 of 12, 3, 4 and 5 nM for EGFR L858R-T790M, Del-T790M, L858R, and EGFR Del, respectively.