Cart
sales@molnova.com
CP-724714 (b)
CAS No. 537705-08-1
CP-724714 (b)( —— )
Catalog No. M14915 CAS No. 537705-08-1
CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | In Stock |
|
| 50MG | 1782 | In Stock |
|
| 100MG | 2250 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCP-724714 (b)
-
NoteResearch use only, not for human use.
-
Brief DescriptionCP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM.
-
DescriptionCP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays. Phase 2.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetEGFR
-
RecptorHER2/ErbB2
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number537705-08-1
-
Formula Weight469.53
-
Molecular FormulaC27H27N5O3
-
Purity>98% (HPLC)
-
SolubilityN/A
-
SMILESCCOC(=O)NC/C=C/C1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OC4=CN=C(C=C4)C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1 Jani JP, et al. Cancer Res, 2007, 67(20), 9887-9893.
2 Feng B, et al. Toxicol Sci, 2009, 108(2), 492-500.
molnova catalog
related products
-
Afatinib
An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively.
-
CGP77675
CGP77675 is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and autophosphorylation of purified Src. CGP77675 exhibits anticancer activity.
-
Peiminine
Peiminine is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
