Hesperidin( Cirantin | Hesperidoside | NSC 44184 )

Catalog No. M14823 CAS No. 520-26-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Hesperidin
Note

Research use only, not for human use.
Brief Description

Hesperidin is a flavanone glycoside found abundantly in citrus fruits.
Description

Hesperidin is a flavanone glycoside found abundantly in citrus fruits.
In Vitro

Cell Viability Assay Cell Line:MG-63 cells Concentration:0, 5, 25, 50, 100, 150, 200 μM Incubation Time:24, 48, 72 hours Result:Led to time-dependent and concentration-dependent cytotoxic effects, with IC50s of 94.3, 78.6 and 63.3 μM at 24, 48 and 72 h, respectively.Apoptosis Analysis Cell Line:MG-63 cells Concentration:0, 5, 50, 150 μM Incubation Time:48 hours Result:Increased the percentage of apoptotic cells from 4.7% to 17.9, 34.6 and 68.3% at the concentration of 0, 5, 50 and 150 μM, respectively.
In Vivo

——
Synonyms

Cirantin | Hesperidoside | NSC 44184
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Cancer
Indication

——

CAS Number

520-26-3
Formula Weight

610.56
Molecular Formula

C28H34O15
Purity

>98% (HPLC)
Solubility

DMSO: 122 mg/mL (199.81 mM)
SMILES

O=C1C[C@@H](C2=CC=C(OC)C(O)=C2)OC3=C1C(O)=CC(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)=C3
Chemical Name

(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one

1.Inderjit, Dakshini KM. J Chem Ecol. 1991 Aug;17(8):1585-9

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