Cart
sales@molnova.com
Propantheline bromide
CAS No. 50-34-0
Propantheline bromide( SC-3171 )
Catalog No. M14705 CAS No. 50-34-0
Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 50MG | 31 | In Stock |
|
| 100MG | 44 | In Stock |
|
| 200MG | 63 | In Stock |
|
| 500MG | 101 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePropantheline bromide
-
NoteResearch use only, not for human use.
-
Brief DescriptionPropantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.
-
DescriptionPropantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.
-
In Vitro——
-
In VivoAnimal Model:Restraint stress-induced bowel dysfunction models in rats Dosage:10-300 mg/kg Administration:Oral administration Result:Decreased the fecal pellet count with ED50 values of 41 mg/kg.Dose-dependently decreased the incidences of diarrhea with ED50 values of 64 mg/kg.
-
SynonymsSC-3171
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
RecptormAChR
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number50-34-0
-
Formula Weight448.4
-
Molecular FormulaC23H30BrNO3
-
Purity>98% (HPLC)
-
SolubilitySoluble in Water
-
SMILES[Br-].CC(C)[N+](C)(CCOC(=O)C1C2=CC=CC=C2OC2=CC=CC=C12)C(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Saitoh H, et al. J Pharmacobiodyn. 1986 Dec; 9(12):1008-14.
molnova catalog
related products
-
Scopolamine butylbro...
Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM.
-
Catestatin
Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Also stimulates mast cell release of histamine via a separate mechanism.
-
Aclidinium bromide
Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.
