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AZD-0837
CAS No. 433937-93-0
AZD-0837( AZD0837 | Atecegatran metoxil )
Catalog No. M14477 CAS No. 433937-93-0
AZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
|
| 50MG | 2142 | Get Quote |
|
| 100MG | 2790 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAZD-0837
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NoteResearch use only, not for human use.
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Brief DescriptionAZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor.
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DescriptionAZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor, has been investigated in phase II studies for prevention of stroke and systemic embolic events in patients with atrial fibrillation (AF).Thrombosis Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsAZD0837 | Atecegatran metoxil
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PathwayAutophagy
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TargetThrombin
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RecptorThrombin
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Research AreaCardiovascular Disease
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IndicationThrombosis
Chemical Information
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CAS Number433937-93-0
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Formula Weight496.896
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Molecular FormulaC22H23ClF2N4O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C([C@H]1N(C([C@@H](C2=CC(OC(F)F)=CC(Cl)=C2)O)=O)CC1)NCC3=CC=C(C(NOC)=N)C=C3
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Chemical Name(S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schützer KM, et al. Eur J Clin Pharmacol. 2010 Sep;66(9):903-10.
2. Lip GY, et al. Thromb Res. 2011 Feb;127(2):91-9.
3. Matsson EM, et al. Mol Pharm. 2013 Nov 4;10(11):4252-62.
4. Deinum J, et al. Thromb Haemost. 2009 Jun;101(6):1051-9.
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