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L-870810
CAS No. 410544-95-5
L-870810( L 870810 | L870810 )
Catalog No. M14410 CAS No. 410544-95-5
A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 963 | Get Quote |
|
| 50MG | 1962 | Get Quote |
|
| 100MG | 2520 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameL-870810
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
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DescriptionA potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties; exhibits broad-spectrum activity against WT and multidrug-resistant HIV-1, HIV-2, and SIV; orally bioavailable.
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In Vitro——
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In Vivo——
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SynonymsL 870810 | L870810
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number410544-95-5
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Formula Weight430.454
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Molecular FormulaC20H19FN4O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=NC(N(CCCC2)S2(=O)=O)=C3C=CC=NC3=C1O)NCC4=CC=C(F)C=C4
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Chemical Name5-(1,1-dioxothiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-8-hydroxy-1,6-naphthyridine-7-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Escin IA;Aescin IA
Escin IA is a triterpene saponin isolated from horse chestnut which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression.
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Reverse transcriptas...
Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.
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HIV p17 Gag 77-85
HIV p17 Gag (77-85) is an attractive target for molecular intervention, because it is involved in the viral replication cycle at both the pre- and postintegration levels. In the present experiments, we targeted p17 by intracellularly expressing a cDNA encoding an Ab to p17.
