Ethyl ferulate( BBR 3222 | NSC 14879 )

Catalog No. M14386 CAS No. 4046-02-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Ethyl ferulate
Note

Research use only, not for human use.
Brief Description

Ethyl ferulate is extracted from angelica, Chuan Xiong.
Description

Ethyl ferulate is extracted from angelica, Chuan Xiong.
In Vitro

Western Blot Analysis Cell Line:RPE cells (induced by 150 μM CoCl2 for 12 h)Concentration:40 μM Incubation Time:2 h Result:Increased Nrf-2 expression and nuclear translocation.Decreased Keap-1 expression, Aand increased HO-1 and NQO-1 expression.Reduced hypoxia-induced HIF-1α and VEGFA expression.
In Vivo

Animal Model:LPS (0.5 mg/kg)-induced acute lung injury mice model Dosage:15 and 30 mg/kg Administration:i.p., twice a day for 5 days Result:Reduced leukocyte infiltration.Reduced MPO activity, mRNA levels and secretion of TNF-α and IL-6.
Synonyms

BBR 3222 | NSC 14879
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

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1.nazaré AC, et al. Molecules. 2014 Jun 17;19(6):8124-39.

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