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XY028-133

CAS No. 2229974-73-4

XY028-133( —— )

Catalog No. M33174 CAS No. 2229974-73-4

XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	546	In Stock
5MG	282	In Stock
10MG	493	In Stock
25MG	847	In Stock
50MG	1460	In Stock
100MG	2539	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

XY028-133
Note

Research use only, not for human use.
Brief Description

XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.
Description

XY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity, which consists of ligands for von Hippel-Lindau and CDK.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PROTACs | CDK
Research Area

——
Indication

——

Chemical Information

CAS Number

2229974-73-4
Formula Weight

1002.23
Molecular Formula

C53H67N11O7S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (49.89 mM; Ultrasonic )
SMILES

CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)CCCCCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)nc2n(C2CCCC2)c1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. JIN, Jian， et al. COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER. Patent. US2017/065027.

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