Carubicin( Carminomycin | Carminomycin I | Carminomicin I )

Catalog No. M14357 CAS No. 39472-31-6

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Product Name

Carubicin
Note

Research use only, not for human use.
Brief Description

Carubicin (Carminomycin) is an apoptosis inducer that targets the Golgi complex.
Description

Carubicin (Carminomycin) is an apoptosis inducer that targets the Golgi complex, induces apoptosis in CCRCC cells by a mechanism independent of p53 or HIF2, and induces cleavage of the Golgi protein p115 and the translocation of its C-terminal fragment to the nucleus.
In Vitro

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In Vivo

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Synonyms

Carminomycin | Carminomycin I | Carminomicin I
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis
Research Area

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Indication

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CAS Number

39472-31-6
Formula Weight

513.499
Molecular Formula

C26H27NO10
Purity

>98% (HPLC)
Solubility

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SMILES

O=C1C2=C(O)C([C@@H](O[C@@H]3O[C@@H](C)[C@@H](O)[C@@H](N)C3)C[C@](O)(C(C)=O)C4)=C4C(O)=C2C(C5=C1C(O)=CC=C5)=O
Chemical Name

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione

1. Woldemichael GM, et al. Cancer Res. 2011 Jan 1;71(1):134-42. 2. Tevyashova AN, et al. J Antibiot (Tokyo). 2004 Feb;57(2):143-50.

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