Cart
sales@molnova.com
ATV399
CAS No. 393834-37-2
ATV399( ATV 399 | ATV-399 )
Catalog No. M14355 CAS No. 393834-37-2
ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase9 levels with IC50 of 3.3 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameATV399
-
NoteResearch use only, not for human use.
-
Brief DescriptionATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase9 levels with IC50 of 3.3 uM.
-
DescriptionATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS; inhibits cleaved caspase-9 activation and subsequent β-cell apoptosis induced by a combination of IL-1β, IFN-γ and high glucose.
-
In Vitro——
-
In Vivo——
-
SynonymsATV 399 | ATV-399
-
PathwayImmunology/Inflammation
-
TargetNOS
-
RecptorNOS
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number393834-37-2
-
Formula Weight465.524
-
Molecular FormulaC24H23N3O5S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=CC=C(OCO2)C2=C1)NC3=CC=C(S(=O)(N4C(C5=CC=CN=C5)CCCC4)=O)C=C3
-
Chemical NameN-(4-((2-(pyridin-3-yl)piperidin-1-yl)sulfonyl)phenyl)benzo[d][1,3]dioxole-5-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Zhong L, et al. Br J Pharmacol. 2018 Jun 11. doi: 10.1111/bph.14388.
molnova catalog
related products
-
Aminoguanidine hydro...
Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor.
-
Rutaevin
Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent.
-
S-Methylisothiourea ...
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock.
