SCH 350581 dihydrochloride
CAS No. 372156-82-6
SCH 350581 dihydrochloride( AD-101 | AD101 )
Catalog No. M14286 CAS No. 372156-82-6
A specific small molecule inhibitor of CCR5, inhibits HIV-1 entry.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameSCH 350581 dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionA specific small molecule inhibitor of CCR5, inhibits HIV-1 entry.
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DescriptionA specific small molecule inhibitor of CCR5, inhibits HIV-1 entry.
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In Vitro——
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In Vivo——
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SynonymsAD-101 | AD101
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number372156-82-6
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Formula Weight575.542
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Molecular FormulaC28H39Cl2F3N4O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(2,4-dimethylpyridin-3-yl)(4-methyl-4-((S)-3-methyl-4-((S)-1-(4-(trifluoromethyl)phenyl)ethyl)piperazin-1-yl)piperidin-1-yl)methanone dihydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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MPG, HIV related
MPG, HIV related is 27-aa peptide, derived from both the nuclear localisation sequence of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41 and is a potent delivery agent for the generalised delivery of nucleic acids and of oligonucleotides into cultured cells.
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NBD-14189
NBD-14189 (NBD14189) is a novel potent HIV-1 entry antagonist with potency as low as 63?nM against some clinical isolates.
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Helichrysetin
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.
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