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TTP 22
CAS No. 329907-28-0
TTP 22( TTP 22 | TTP-22 | TTP22 )
Catalog No. M14092 CAS No. 329907-28-0
TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 95 | In Stock |
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| 5MG | 70 | In Stock |
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| 10MG | 106 | In Stock |
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| 25MG | 207 | In Stock |
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| 50MG | 276 | In Stock |
|
| 100MG | 399 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTTP 22
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NoteResearch use only, not for human use.
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Brief DescriptionTTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM.
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DescriptionTTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM; shows selectivity for CK2 over JNK3, ROCK1, and MET(IC50> 10 uM).
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In VitroTTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM.
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In Vivo——
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SynonymsTTP 22 | TTP-22 | TTP22
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PathwayMetabolic Enzyme/Protease
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TargetCasein Kinase
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RecptorCK2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number329907-28-0
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Formula Weight330.42
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Molecular FormulaC16H14N2O2S2
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mg/mL
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SMILESO=C(O)CCSC1=C(C(C2=CC=C(C)C=C2)=CS3)C3=NC=N1
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Chemical Name3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-propanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Golub AG, et al. Eur J Med Chem. 2011 Mar;46(3): 870-6.
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