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Chlorogenic Acid
CAS No. 327-97-9
Chlorogenic Acid( 3-O-Caffeoylquinic acid | Heriguard | NSC 407296 )
Catalog No. M14069 CAS No. 327-97-9
Chlorogenic acid(NSC-407296; 3-O-Caffeoylquinic acid) is one of the most abundant polyphenols in the human diet, has been reported to inhibit Y cell growth and a major anti-inflammatory constituent of lonicerae flos extract.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 52 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | 47 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameChlorogenic Acid
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NoteResearch use only, not for human use.
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Brief DescriptionChlorogenic acid(NSC-407296; 3-O-Caffeoylquinic acid) is one of the most abundant polyphenols in the human diet, has been reported to inhibit Y cell growth and a major anti-inflammatory constituent of lonicerae flos extract.
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DescriptionChlorogenic acid(NSC-407296; 3-O-Caffeoylquinic acid) is one of the most abundant polyphenols in the human diet, has been reported to inhibit Y cell growth and a major anti-inflammatory constituent of lonicerae flos extract.
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In Vitro——
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In VivoAnimal Model:Experimental reflux esophagitis (RE) in ratsDosage:10, 30, 100 mg/kg Administration:p.o.Result:Reduced esophageal lipid peroxidation (marker: MDA) and increased the reduced glutathione/oxidized glutathione ratio. Inhibited the increases in the serum level of TNF-α, and expressions of iNOS and COX-2 protein.Animal Model:LPS/GalN-challenged mice Dosage:10 mg/kg Administration:i.v.Result:Increased survival rates of LPS/GalN-intoxicated mice.Inhibited LPS/GalN-induced phosphorylation of NF-κB p65 or c-Jun, without affecting p-IRF3 levels in the liver lobules.
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Synonyms3-O-Caffeoylquinic acid | Heriguard | NSC 407296
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number327-97-9
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Formula Weight354.32
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Molecular FormulaC16H18O9
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Purity>98% (HPLC)
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SolubilityEthanol: 71 mg/mL (200.38 mM); Water: 18 mg/mL (50.8 mM); DMSO: 71 mg/mL (200.38 mM)
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SMILESO=C([C@@]1(O)C[C@@H](OC(/C=C\C2=CC=C(O)C(O)=C2)=O)[C@H](O)[C@H](O)C1)O
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Chemical Name(1S,3R,4R,5R)-3-{[(2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Illing EA, et al. Otolaryngol Head Neck Surg. 2015 Aug;153(2):291-7.
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