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Indiplon
CAS No. 325715-02-4
Indiplon( NBI-34060 )
Catalog No. M14055 CAS No. 325715-02-4
A potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 56 | Get Quote |
|
| 5MG | 80 | Get Quote |
|
| 10MG | 114 | Get Quote |
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| 25MG | 206 | Get Quote |
|
| 50MG | 371 | Get Quote |
|
| 100MG | 611 | Get Quote |
|
| 200MG | 1014 | Get Quote |
|
| 500MG | 2148 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIndiplon
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NoteResearch use only, not for human use.
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Brief DescriptionA potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site.
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DescriptionA potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site (Ki values are 1.2 and 1.7 nM in rat frontal cortex and cerebellum respectively); potentiates the GABA-activated chloride current in recombinant GABA(A) receptors in a dose-dependent and reversible manner in 293 cells, 10-fold selective for α1 subunit-containing receptors over GABA(A) receptors containing α2, α3, or α5 subunits. Sleep Disorder Phase 3 Clinical.
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In Vitro——
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In Vivo——
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SynonymsNBI-34060
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGAT
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Research AreaNeurological Disease
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IndicationSleep Disorder
Chemical Information
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CAS Number325715-02-4
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Formula Weight376.4316
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Molecular FormulaC20H16N4O2S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(N(C)C1=CC=CC(C2=CC=NC3=C(C(C4=CC=CS4)=O)C=NN23)=C1)=O
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Chemical NameAcetamide, N-methyl-N-[3-[3-(2-thienylcarbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lankford A. Neuropsychiatr Dis Treat. 2007 Dec;3(6):765-73.
2. Marrs JC. Ann Pharmacother. 2008 Jul;42(7):1070-9.
3. Petroski RE, et al. J Pharmacol Exp Ther. 2006 Apr;317(1):369-77.
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