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Hexamethylene bisacetamide
CAS No. 3073-59-4
Hexamethylene bisacetamide( HMBA | NSC 95580 )
Catalog No. M13980 CAS No. 3073-59-4
A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
|
| 50MG | 37 | In Stock |
|
| 100MG | 51 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 120 | In Stock |
|
| 1G | 179 | In Stock |
|
Biological Information
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Product NameHexamethylene bisacetamide
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NoteResearch use only, not for human use.
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Brief DescriptionA cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.
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DescriptionA cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade; causes MEL cell differentiation by acting as a selective BD2 (bromodomain 2) inhibitor, kills Myc-induced lymphoma cells in vitro and in vivo; also is a small molecule inducer of HEXIM1 expression, inhibits the metastasis of breast cancer to lung in PyMT mice.
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In Vitro——
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In Vivo——
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SynonymsHMBA | NSC 95580
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number3073-59-4
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Formula Weight200.28
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Molecular FormulaC10H20N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (124.83 mM)
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SMILESCC(NCCCCCCNC(C)=O)=O
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Chemical Name1,6-Hexanebisacetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ketchart W, et al. Oncogene. 2013 Aug 15;32(33):3829-39.
2. Nilsson LM, et al. Cancer Res. 2016 Apr 15;76(8):2376-83.
3. Dey A, et al. Cell Cycle. 2008 Dec;7(23):3759-67.
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