Hexamethylene bisacetamide( HMBA | NSC 95580 )

Catalog No. M13980 CAS No. 3073-59-4

A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	29	In Stock
50MG	37	In Stock
100MG	51	In Stock
200MG	Get Quote	In Stock
500MG	120	In Stock
1G	179	In Stock

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Biological Information

Product Name

Hexamethylene bisacetamide
Note

Research use only, not for human use.
Brief Description

A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.
Description

A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade; causes MEL cell differentiation by acting as a selective BD2 (bromodomain 2) inhibitor, kills Myc-induced lymphoma cells in vitro and in vivo; also is a small molecule inducer of HEXIM1 expression, inhibits the metastasis of breast cancer to lung in PyMT mice.
In Vitro

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In Vivo

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Synonyms

HMBA | NSC 95580
Pathway

Chromatin/Epigenetic
Target

Bromodomain
Recptor

Bromodomain
Research Area

——
Indication

——

Chemical Information

CAS Number

3073-59-4
Formula Weight

200.28
Molecular Formula

C10H20N2O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (124.83 mM)
SMILES

CC(NCCCCCCNC(C)=O)=O
Chemical Name

1,6-Hexanebisacetamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ketchart W, et al. Oncogene. 2013 Aug 15;32(33):3829-39. 2. Nilsson LM, et al. Cancer Res. 2016 Apr 15;76(8):2376-83. 3. Dey A, et al. Cell Cycle. 2008 Dec;7(23):3759-67.

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