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SJ830599
CAS No. 2215098-23-8
SJ830599( SJ 830599 )
Catalog No. M13530 CAS No. 2215098-23-8
SJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameSJ830599
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NoteResearch use only, not for human use.
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Brief DescriptionSJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1.
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DescriptionSJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1; demonstrates cytotoxicity against several pediatric cancer cell lines with EC50 values (HD-MB03 EC50=480 nM) comparable to BET inhibitor (BETi) clinical candidates.
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In Vitro——
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In Vivo——
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SynonymsSJ 830599
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number2215098-23-8
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Formula Weight356.422
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Molecular FormulaC20H24N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameIsopropyl ((2S,4R)-1-acetyl-6-(furan-2-yl)-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)carbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shadrick WR, et al. Bioorg Med Chem. 2018 Jan 1;26(1):25-36.
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