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Carbamazepine
CAS No. 298-46-4
Carbamazepine( Carbamazepine, Tegretol, Epitol )
Catalog No. M13912 CAS No. 298-46-4
Carbamazepine, a sodium channel blocker, is an anticonvulsant drug.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 40 | In Stock |
|
| 100MG | 34 | In Stock |
|
| 200MG | 39 | In Stock |
|
| 500MG | 47 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCarbamazepine
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NoteResearch use only, not for human use.
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Brief DescriptionCarbamazepine, a sodium channel blocker, is an anticonvulsant drug.
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DescriptionCarbamazepine, a sodium channel blocker, is an anticonvulsant drug.
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In VitroWestern Blot Analysis Cell Line:3T3-L1 pre-adipocytes Concentration:0-500 μM Incubation Time:10 days Result:Decreased PPAR-γ and C/EPB-α protein levels.Increased ERK 1/2 phosphorylation after a 10?min exposure, and also increased p38 MAPK phosphorylation.
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In VivoAnimal Model:70% Partial hepatectomy treated mice Dosage:250 mg/kg Administration:p.o.Result:Recoverd liver to body weight ratio.Increased the number of BrdU-positive nuclei, Increased PCNA protein.Increased mRNA levels of ccne2 and ccna2.
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SynonymsCarbamazepine, Tegretol, Epitol
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorSodium Channel
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number298-46-4
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Formula Weight236.27
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Molecular FormulaC15H12N2O
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Purity>98% (HPLC)
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SolubilityEthanol: 18 mg/mL (76.18 mM); DMSO: 47 mg/mL (198.92 mM)
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SMILESO=C(C1=CC2=CC=CC=C2NC3=CC=CC=C13)N
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Chemical Namebenzo[b][1]benzazepine-11-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Willow M, et al. Mol Pharmacol, 1982, 22(3), 627-635.
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