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(S)-Timolol maleate
CAS No. 26921-17-5
(S)-Timolol maleate( Timolol maleate )
Catalog No. M13824 CAS No. 26921-17-5
A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name(S)-Timolol maleate
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NoteResearch use only, not for human use.
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Brief DescriptionA potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.
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DescriptionA potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.Hypertension Approved.
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In Vitro——
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In Vivo——
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SynonymsTimolol maleate
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PathwayGPCR/G Protein
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TargetAdrenergic Receptor
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Recptorβ1-adrenergicreceptor|β2-adrenergicreceptor
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Research AreaCardiovascular Disease
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IndicationHypertension
Chemical Information
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CAS Number26921-17-5
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Formula Weight432.4918
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Molecular FormulaC17H28N4O7S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 4.4 mg/mL
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SMILESCC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O.C(=C\C(=O)O)\C(=O)O
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Chemical Name2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mandagere AK, et al. J Med Chem. 2002;45(2):304-11.
2. Aggarwal D, et al. Int J Pharm. 2005 Feb 16;290(1-2):155-9.
3. Borok J, et al. Br J Dermatol. 2017 Aug 3. doi: 10.1111/bjd.15865.
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