Cyclo(RGDyK) trifluoroacetate

Research use only, not for human use.

Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM.

Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM; a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including αvβ3.(In Vitro):Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).

Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5(IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).

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Cyclic Arg-Gly-Asp-D-Tyr-Lys

Cell Cycle/DNA Damage

Integrin

αVβ3integrin

Cardiovascular Disease

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250612-42-1

847.72

C31H43F6N9O12

>98% (HPLC)

DMSO: 94 mg/mL (110.9 mM)Water: 94 mg/mL (110.9 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )

C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=C(C=C2)O)CC(=O)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O

Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl), bis(trifluoroacetate) (salt) (9CI)

(-20℃)

With Ice Pack

≥ 2 years