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KDM-IN-6
CAS No. 2169272-46-0
KDM-IN-6( —— )
Catalog No. M13462 CAS No. 2169272-46-0
KDM-IN-6 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM,respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
|
| 50MG | 2502 | Get Quote |
|
| 100MG | 3330 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameKDM-IN-6
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NoteResearch use only, not for human use.
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Brief DescriptionKDM-IN-6 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM,respectively.
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DescriptionKDM-IN-6 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM,respectively; displays >75 fold selectivity towards KDM2A/7A versus other JmjC lysine demethylase; shows cytotoxicity towards HeLa and HAP1 cells with EC50 of 22 uM and 7.1 uM respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorHistone Demethylase
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Research Area——
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Indication——
Chemical Information
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CAS Number2169272-46-0
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Formula Weight506.694
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Molecular FormulaC33H38N4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 200 mg/mL (394.73 mM)
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SMILESCC(N([C@@H](C1=CN=CC(CCCCCCCN2CCCC2)=C1)[C@@]3(C4=CC=CC=C4)C#N)C5=C3C=CC=C5)=O
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Chemical Name(2S,3S)-1-acetyl-3-phenyl-2-(5-(7-(pyrrolidin-1-yl)heptyl)pyridin-3-yl)indoline-3-carbonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gerken P, et al. Angew Chem Int Ed Engl. 2017 Oct 4. doi: 10.1002/anie.201706788.
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