Cart
sales@molnova.com
SU-909
CAS No. 2126749-48-0
SU-909( SU909 | SU 909 | IKKα-IN-48 )
Catalog No. M13383 CAS No. 2126749-48-0
SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSU-909
-
NoteResearch use only, not for human use.
-
Brief DescriptionSU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM.
-
DescriptionSU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM); inhibits FCS-stimulated phosphorylation of p100 in U2OS cells with IC50 of 8.8 uM, inhibits the noncanonical NF-kB pathway without affecting IKKβ-dependent IKappa-Bα loss in the canonical pathway.
-
In Vitro——
-
In Vivo——
-
SynonymsSU909 | SU 909 | IKKα-IN-48
-
PathwayImmunology/Inflammation
-
TargetIκB kinase (IKK)
-
RecptorIκB kinase (IKK)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2126749-48-0
-
Formula Weight314.323
-
Molecular FormulaC13H10N6O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name4-(2-Amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzenesulfonamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Anthony NG, et al. J Med Chem. 2017 Aug 24;60(16):7043-7066.
molnova catalog
related products
-
LY2409881 trihydroch...
LY2409881 trihydrochloride is a novel selective inhibitor of IKK2 with IC50 of 30 nM; IC50 for IKK1 and other common kinases is at least one log higher.
-
PS-1145
A specific IκB kinase (IKK) inhibitor with IC50 of 88 nM.
-
ACHP
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β.
