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BTX161
CAS No. 2052301-24-1
BTX161( BTX-161 )
Catalog No. M13185 CAS No. 2052301-24-1
BTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1341 | In Stock |
|
| 100MG | 2124 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBTX161
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NoteResearch use only, not for human use.
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Brief DescriptionBTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53.
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DescriptionBTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53, while stabilizing the p53 antagonist MDM2; upregulates all the Wnt targets including MYC and does not affect MDM2 mRNA expression.
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In Vitro——
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In Vivo——
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SynonymsBTX-161
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PathwayMetabolic Enzyme/Protease
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TargetCasein Kinase
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RecptorCasein Kinase
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Research Area——
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Indication——
Chemical Information
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CAS Number2052301-24-1
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Formula Weight272.304
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Molecular FormulaC15H16N2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (91.81 mM)
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SMILESCC1=C2CN(C(=O)C2=CC=C1)C3CCCC(=O)NC3=O
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Chemical Name(S)-3-(4-methyl-1-oxoisoindolin-2-yl)azepane-2,7-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Minzel W, et al. Cell. 2018 Aug 20. pii: S0092-8674(18)30973-5. doi: 10.1016/j.cell.2018.07.045.
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