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Windorphen

CAS No. 19881-70-0

Windorphen( —— )

Catalog No. M13107 CAS No. 19881-70-0

A potent, selective inhibitor of p300 histone acetyltransferase (IC50=4.2 uM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	29	In Stock
10MG	34	In Stock
25MG	61	In Stock
50MG	88	In Stock
100MG	127	In Stock
200MG	183	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Windorphen
Note

Research use only, not for human use.
Brief Description

A potent, selective inhibitor of p300 histone acetyltransferase (IC50=4.2 uM).
Description

A potent, selective inhibitor of p300 histone acetyltransferase (IC50=4.2 uM); displays >10-fold selectivity over other histone acetyltransferases; inhibits Wnt3a-inducible TOPFLASH-luciferase activity with IC50 of 1.5 uM, exhibits remarkable specificity toward β-catenin-1 function and selectively blocks the Wnt signal required for ventral development; robustly and selectively kills cancer cells that harbor Wnt-activating mutations.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

HAT
Recptor

HAT
Research Area

——
Indication

——

Chemical Information

CAS Number

19881-70-0
Formula Weight

302.75
Molecular Formula

C17H15ClO3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (206.44 mM)
SMILES

COC1=CC=C(C=C1)C(=C(C2=CC=C(C=C2)OC)Cl)C=O
Chemical Name

(Z)-3-chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hao J, et al. Cell Rep. 2013 Sep 12;4(5):898-904.

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