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MTX-211
CAS No. 1952236-05-3
MTX-211( MTX 211 )
Catalog No. M13055 CAS No. 1952236-05-3
A first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 150 | In Stock |
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| 5MG | 294 | In Stock |
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| 10MG | 447 | In Stock |
|
| 25MG | 737 | In Stock |
|
| 50MG | 1017 | In Stock |
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| 100MG | 1377 | In Stock |
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| 500MG | 2673 | In Stock |
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| 1G | Get Quote | In Stock |
|
| 1 mL x 10 mM in DMSO | 180 | In Stock |
|
| 2MG | 91 | In Stock |
|
| 5MG | 170 | In Stock |
|
| 10MG | 275 | In Stock |
|
| 25MG | 464 | In Stock |
|
| 50MG | 626 | In Stock |
|
| 100MG | 830 | In Stock |
|
| 200MG | 1135 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMTX-211
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NoteResearch use only, not for human use.
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Brief DescriptionA first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases.
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DescriptionA first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with demonstrated in vivo anticancer activity against multiple KRAS mutant colorectal tumors; shows limited off-target toxicity and a broad therapeutic window.
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In VitroMTX-211 (MOL211) has inhibitory activity for both EGFR and PI3K Alpha with IC50 values of ＜100 nM.
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In Vivo——
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SynonymsMTX 211
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorEGFR|PI3K
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Research Area——
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Indication——
Chemical Information
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CAS Number1952236-05-3
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Formula Weight478.323
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Molecular FormulaC20H14Cl2FN5O2S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥100 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESCS(=O)(NC1=CC(C2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2)=CN=C1Cl)=O
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Chemical NameMethanesulfonamide, N-[2-chloro-5-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-3-pyridinyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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