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Otamixaban
CAS No. 193153-04-7
Otamixaban( FXV-673 )
Catalog No. M13026 CAS No. 193153-04-7
A potent and selective factor Xa (FXa) inhibitor with Ki of 0.4 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 284 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameOtamixaban
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective factor Xa (FXa) inhibitor with Ki of 0.4 nM.
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DescriptionA potent and selective factor Xa (FXa) inhibitor with Ki of 0.4 nM; shows >1,000-fold selectivity over thrombin, activated protein C (aPC), plasmin, and tissue-plasminogen activator (t-PA); dose-dependently prolongs the time to vessel occlusion and inhibits thrombus formation in canine models of thrombosis.Thrombosis Phase 3 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsFXV-673
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PathwayMetabolic Enzyme/Protease
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TargetFactor Xa
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RecptorFactor Xa
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Research AreaCardiovascular Disease
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IndicationThrombosis
Chemical Information
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CAS Number193153-04-7
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Formula Weight446.4984
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Molecular FormulaC25H26N4O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESC[C@@H](NC(C1=CC=C(C2=CC=[N+]([O-])C=C2)C=C1)=O)[C@@H](CC3=CC=CC(C(N)=N)=C3)C(OC)=O
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Chemical NameBenzenepropanoic acid, 3-(aminoiminomethyl)-.alpha.-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]-, methyl ester, (.alpha.R)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Guertin KR, et al. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1671-4.
2. Chu V, et al. Thromb Res. 2001 Aug 15;103(4):309-24.
3. Rebello SS, et al. J Cardiovasc Pharmacol. 2001 Aug;38(2):288-97.
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