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KDM5A-IN-1
CAS No. 1905481-36-8
KDM5A-IN-1( KDM5A-IN-1 | KDM5A IN 1 | KDM5AIN1 | KDM5A inhibitor-1 )
Catalog No. M12988 CAS No. 1905481-36-8
An inhibitor of histone demethylase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 260 | Get Quote |
|
| 50MG | 1116 | Get Quote |
|
| 100MG | 1566 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
| 1 mL x 10 mM in DMSO | 376 | In Stock |
|
| 5MG | 260 | In Stock |
|
| 50MG | 1116 | In Stock |
|
| 100MG | 1566 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKDM5A-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionAn inhibitor of histone demethylase.
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DescriptionAn inhibitor of histone demethylase.
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In Vitro——
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In VivoAnimal Model:Female CD-1 miceDosage:5 mg/kg Administration:Oral administration (Pharmacokinetic study) Result:Moderate clearance (28 mL/min/kg) in mice with good oral bioavailability (F% 34), and showed remarkably low plasma protein binding in mice (40%).
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SynonymsKDM5A-IN-1 | KDM5A IN 1 | KDM5AIN1 | KDM5A inhibitor-1
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorHistone Demethylase
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1905481-36-8
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Formula Weight290.3608
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Molecular FormulaC15H22N4O2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1CC1)N[C@@H]2CCN(C(C3=CC(C(C)C)=NN3)=O)C2
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Chemical NameCyclopropanecarboxamide, N-[(3R)-1-[[5-(1-methylethyl)-1H-pyrazol-3-yl]carbonyl]-3-pyrrolidinyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kwong Wah LAI, et al. WO 2016057924 A1 20160414.
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