Cart
sales@molnova.com
KDM5A-IN-1
CAS No. 1905481-36-8
KDM5A-IN-1( KDM5A-IN-1 | KDM5A IN 1 | KDM5AIN1 | KDM5A inhibitor-1 )
Catalog No. M12988 CAS No. 1905481-36-8
An inhibitor of histone demethylase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 376 | In Stock |
|
| 5MG | 260 | In Stock |
|
| 50MG | 1116 | In Stock |
|
| 100MG | 1566 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameKDM5A-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionAn inhibitor of histone demethylase.
-
DescriptionAn inhibitor of histone demethylase.
-
In Vitro——
-
In VivoAnimal Model:Female CD-1 miceDosage:5 mg/kg Administration:Oral administration (Pharmacokinetic study) Result:Moderate clearance (28 mL/min/kg) in mice with good oral bioavailability (F% 34), and showed remarkably low plasma protein binding in mice (40%).
-
SynonymsKDM5A-IN-1 | KDM5A IN 1 | KDM5AIN1 | KDM5A inhibitor-1
-
PathwayChromatin/Epigenetic
-
TargetHistone Demethylase
-
RecptorHistone Demethylase
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1905481-36-8
-
Formula Weight290.3608
-
Molecular FormulaC15H22N4O2
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(C1CC1)N[C@@H]2CCN(C(C3=CC(C(C)C)=NN3)=O)C2
-
Chemical NameCyclopropanecarboxamide, N-[(3R)-1-[[5-(1-methylethyl)-1H-pyrazol-3-yl]carbonyl]-3-pyrrolidinyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kwong Wah LAI, et al. WO 2016057924 A1 20160414.
molnova catalog
related products
-
P3FI-63
P3FI-63 is a selective KDM3B inhibitor (IC50: 7 μM) with antitumor activity for the study of fusion-positive rhabdomyosarcoma and other transcriptionally addictive cancers.
-
GSK-2879552
A potent, selective irreversible inhibitor of LSD1 with Ki app of 1.7 uM.
-
ORY-1001 dihydrochlo...
ORY-1001 dihydrochloride (RG-6016, Ladademstat) is a highly potent, selective inhibitor of lysine-specific demethylase KDM1A (LSD1) with IC50 of 18 nM.
