Traxoprodil mesylate

Research use only, not for human use.

A potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit; potently protects cultured hippocampal neurons from glutamate toxicity (IC50=10 nM).

A potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit; potently protects cultured hippocampal neurons from glutamate toxicity (IC50=10 nM), dramatically reduces both the open dwell-time and frequency of channel opening of NR1/NR2B-containing receptors, but only modestly inhibits NR1/NR2A and NR1/NR2C channel activity; exhibits neuroprotective, analgesic, and anti-Parkinsonian effects in animal studies.Depression Phase 2 Discontinued.

——

——

CP-101606 mesylate

Membrane Transporter/Ion Channel

iGluR

iGluR

Neurological Disease

Depression

188591-67-5

423.524

C21H29NO6S

>98% (HPLC)

——

CC(C(C1=CC=C(C=C1)O)O)N2CCC(CC2)(C3=CC=CC=C3)O.CS(=O)(=O)O

(1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol mesylate

(-20℃)

With Ice Pack

≥ 2 years