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Solriamfetol hydrochloride

CAS No. 178429-62-4

Solriamfetol hydrochloride( JZP-110 | R-228060 | ADX-N05 | YKP-10A )

Catalog No. M12688 CAS No. 178429-62-4

Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Solriamfetol hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively.
  • Description
    Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively; a wake-promoting agent with dopaminergic and noradrenergic activity.Sleep Disorder Phase 3 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    JZP-110 | R-228060 | ADX-N05 | YKP-10A
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Monoamine Transporter
  • Recptor
    Monoamine Transporter
  • Research Area
    Neurological Disease
  • Indication
    Sleep Disorder

Chemical Information

  • CAS Number
    178429-62-4
  • Formula Weight
    230.692
  • Molecular Formula
    C10H15ClN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    NC(OC[C@H](N)CC1=CC=CC=C1)=O.[H]Cl
  • Chemical Name
    (R)-2-amino-3-phenylpropyl carbamate hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bogan RK, et al. Sleep Med. 2015 Sep;16(9):1102-8.
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