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MAP4K4-IN-11e

CAS No. 1774346-60-9

MAP4K4-IN-11e( MAP4K4 inhibitor 11e )

Catalog No. M12671 CAS No. 1774346-60-9

A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM.

Purity : >98% (HPLC)

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Biological Information

Product Name

MAP4K4-IN-11e
Note

Research use only, not for human use.
Brief Description

A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM.
Description

A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases; is active at much lower concentration in the cellular neurite outgrowth assay and may exhibit better pharmacokinetic properties.
In Vitro

——
In Vivo

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Synonyms

MAP4K4 inhibitor 11e
Pathway

MAPK/ERK Signaling
Target

MAP4K
Recptor

MAP4K
Research Area

——
Indication

——

Chemical Information

CAS Number

1774346-60-9
Formula Weight

301.342
Molecular Formula

C17H19NO4
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

3-hexanoyl-4-hydroxy-5-(4-hydroxyphenyl)pyridin-2(1H)-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Schr?der P, et al. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12398-403.

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