Valganciclovir hydrochloride

CAS No. 175865-59-5

Valganciclovir hydrochloride( Ro 107-9070/194 | Valcyte )

Catalog No. M12657 CAS No. 175865-59-5

Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 30 In Stock
10MG 29 In Stock
25MG 51 In Stock
50MG 83 In Stock
100MG 129 In Stock
200MG 184 In Stock
500MG 323 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Valganciclovir hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir.
  • Description
    Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.
  • In Vitro
    Cell Viability Assay Cell Line:A549 cells Concentration:500 μM Incubation Time:5 days, 7days Result:Showed EC50 values ranged from 120.5 μM (Ad4) to 244.4 μM (Ad6).Showed IC50 values was calculated to be 11.74 mM at 7 days post-infection.
  • In Vivo
    Animal Model:Immunosuppressed hamstersDosage:200 mg/kg Administration:Oral gavage (p.o.)Result:Resulted in significantly smaller magnitude of weight loss for all groups.Reduced the liver pathology.
  • Synonyms
    Ro 107-9070/194 | Valcyte
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CMV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    175865-59-5
  • Formula Weight
    390.82
  • Molecular Formula
    C14H23ClN6O5
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 78 mg/mL (199.58 mM); DMSO: 78 mg/mL (199.58 mM)
  • SMILES
    CC(C)[C@H](N)C(OCC(OCN1C=NC2=C1NC(N)=NC2=O)CO)=O.[H]Cl
  • Chemical Name
    [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] (2S)-2-amino-3-methylbutanoate hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sugawara M, et al. J Pharm Sci, 2000, 89(6), 781-789.
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