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Lacosamide
CAS No. 175481-36-4
Lacosamide( Erlosamide | SPM 927 | ADD 234037 )
Catalog No. M12653 CAS No. 175481-36-4
An anticonvulsant compound that enhances the slow inactivation of voltage-gated sodium channels without affecting the fast inactivation of voltage-gated sodium channels.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameLacosamide
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NoteResearch use only, not for human use.
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Brief DescriptionAn anticonvulsant compound that enhances the slow inactivation of voltage-gated sodium channels without affecting the fast inactivation of voltage-gated sodium channels.
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DescriptionAn anticonvulsant compound that enhances the slow inactivation of voltage-gated sodium channels without affecting the fast inactivation of voltage-gated sodium channels; launched for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.Epilepsy Approved.
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In Vitro——
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In Vivo——
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SynonymsErlosamide | SPM 927 | ADD 234037
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorSodium Channel
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Research AreaNeurological Disease
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IndicationEpilepsy
Chemical Information
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CAS Number175481-36-4
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Formula Weight250.294
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Molecular FormulaC13H18N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NCC1=CC=CC=C1)[C@H](NC(C)=O)COC
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Chemical Name(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hao JX, et al. Eur J Pharmacol. 2006 Dec 28;553(1-3):135-40.
2. Lees G, et al. Neuropharmacology. 2006 Jan;50(1):98-110.
3. Duncan GE, et al. Epilepsy Res. 2005 Oct-Nov;67(1-2):81-7.
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