Cart
sales@molnova.com
Cerulenin
CAS No. 17397-89-6
Cerulenin( Cerulenin | Helicocerin | Cephalosporium caerulens | AC1NQZF4 | EINECS 241-424-8 )
Catalog No. M12641 CAS No. 17397-89-6
An antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 178 | In Stock |
|
| 10MG | 265 | In Stock |
|
| 25MG | 447 | In Stock |
|
| 50MG | 677 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCerulenin
-
NoteResearch use only, not for human use.
-
Brief DescriptionAn antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells.
-
DescriptionAn antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells; induces pro-survival, Akt and ERK activation, in serum-deprived KRAS mutant cancer cells; causes a dose-dependent decrease in HER2/neu protein levels in breast cancer cells.
-
In Vitro——
-
In Vivo——
-
SynonymsCerulenin | Helicocerin | Cephalosporium caerulens | AC1NQZF4 | EINECS 241-424-8
-
PathwayMicrobiology/Virology
-
TargetFungal
-
RecptorFungal
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number17397-89-6
-
Formula Weight223.27
-
Molecular FormulaC12H17NO3
-
Purity>98% (HPLC)
-
SolubilityDMSO : 100 mg/mL 447.89 mM
-
SMILESCC=CCC=CCCC(=O)C1C(O1)C(=O)N
-
Chemical Name(2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Gouw AM, et al. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4300-4305.
2. Yellen P, et al. Cancer Lett. 2014 Oct 28;353(2):258-63.
3. Menendez JA, et al. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10715-20.
molnova catalog
related products
-
Terbinafine hydrochl...
A synthetic antifungal agent that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.
-
Nystatin
A polyene antifungal antibiotic that works by disrupting the cell membrane of the fungal cells.
-
Fosmanogepix
Fosmanogepix (APX001 prodrug) is a novel antifungal agent.
