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BMS-242
CAS No. 1675204-51-9
BMS-242( BMS 242 | BMS242 )
Catalog No. M12561 CAS No. 1675204-51-9
A potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBMS-242
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NoteResearch use only, not for human use.
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Brief DescriptionA potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.
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DescriptionA potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.
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In Vitro——
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In Vivo——
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SynonymsBMS 242 | BMS242
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PathwayImmunology/Inflammation
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TargetPD-1/PD-L1
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RecptorPD-1/PD-L1
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Research Area——
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Indication——
Chemical Information
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CAS Number1675204-51-9
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Formula Weight449.591
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Molecular FormulaC28H35NO4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)[C@@H](NCC1=C(OC)C=C(OCC2=C(C)C(C3=CC=CC=C3)=CC=C2)C=C1OC)CO
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Chemical Name(R)-2-((2,6-dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)amino)-3-methylbutan-1-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.
2. Zak KM, et al. Oncotarget. 2016 May 24;7(21):30323-35.
3. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).
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