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Phorbol 12-myristate 13-acetate

CAS No. 16561-29-8

Phorbol 12-myristate 13-acetate( PMA )

Catalog No. M12527 CAS No. 16561-29-8

A PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 117 In Stock
5MG 85 In Stock
10MG 123 In Stock
25MG 202 In Stock
50MG 293 In Stock
100MG 435 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Phorbol 12-myristate 13-acetate
  • Note
    Research use only, not for human use.
  • Brief Description
    A PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.
  • Description
    A PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms; a potent tumor promoter often employed in biomedical research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PMA
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKC
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    16561-29-8
  • Formula Weight
    616.825
  • Molecular Formula
    C36H56O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 62 mg/mL
  • SMILES
    CCCCCCCCCCCCCC(O[C@]1([H])[C@@]([C@@]2(O)[C@@]([C@]([C@@]13OC(C)=O)([H])C3(C)C)([H])C=C(CO)C[C@@]4(O)[C@@]2([H])C=C(C4=O)C)([H])C)=O
  • Chemical Name
    Tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xu F, et al. Br J Pharmacol. 2003 Sep;140(2):413-21. 2. Blumberg PM, et al. Cancer Res. 1988 Jan 1;48(1):1-8. 3. Niedel JE, et al. Proc Natl Acad Sci U S A. 1983 Jan;80(1):36-40.
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